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1

Chemical control of protein stability and function in living mice

Banaszynski, Laura A, Sellmyer, Mark A, Contag, Christopher H, Wandless, Thomas J, Thorne, Steve H

Journal:

Nature Medicine

Year:

2008

Language:

english

File:

PDF, 298 KB

english, 2008

2

SIK1 is a class II HDAC kinase that promotes survival of skeletal myocytes

Berdeaux, Rebecca, Goebel, Naomi, Banaszynski, Laura, Takemori, Hiroshi, Wandless, Thomas, Shelton, G Diane, Montminy, Marc

Journal:

Nature Medicine

Year:

2007

Language:

english

File:

PDF, 440 KB

english, 2007

3

A Simple and Efficient Method for the Preparation of Hindered Alkyl−Aryl Ethers

Woiwode, Thomas F., Rose, Christoph, Wandless, Thomas J.

Journal:

Journal of Organic Chemistry

Year:

1998

Language:

english

File:

PDF, 40 KB

english, 1998

4

Destabilizing Domains Derived from the Human Estrogen Receptor

Miyazaki, Yusuke, Imoto, Hiroshi, Chen, Ling-chun, Wandless, Thomas J.

Journal:

Journal of the American Chemical Society

Year:

2012

Language:

english

File:

PDF, 590 KB

english, 2012

5

Authors’ Response

Thomas, Neil P., Kankate, Raghu, Wandless, Felicity, Pandit, Hemant

Journal:

American Journal of Sports Medicine

Year:

2006

Language:

english

File:

PDF, 38 KB

english, 2006

6

The Enantioselective Synthesis of Phomopsin B

Joshua S. Grimley, Andrew M. Sawayama, Hiroko Tanaka, Michelle M. Stohlmeyer, Thomas F. Woiwode, Thomas J. Wandless

Journal:

Angewandte Chemie

Year:

2007

Language:

english

File:

PDF, 321 KB

english, 2007

7

The Enantioselective Synthesis of Phomopsin B

Joshua S. Grimley, Andrew M. Sawayama, Hiroko Tanaka, Michelle M. Stohlmeyer, Thomas F. Woiwode, Thomas J. Wandless

Journal:

Angewandte Chemie International Edition

Year:

2007

Language:

english

File:

PDF, 322 KB

english, 2007

8

Rescue of Degradation-Prone Mutants of the FK506-Rapamycin Binding (FRB) Protein with Chemical Ligands

Kryn Stankunas, J. Henri Bayle, James J. Havranek, Thomas J. Wandless, David Baker, Gerald R. Crabtree, Jason E. Gestwicki

Journal:

Year:

2007

Language:

english

File:

PDF, 579 KB

english, 2007

9

ChemInform Abstract: A Simple and Efficient Method for the Preparation of Hindered Alkyl—Aryl Ethers.

Thomas F. Woiwode, Christoph Rose, Thomas J. Wandless

Journal:

Year:

1999

File:

PDF, 29 KB

1999

10

ChemInform Abstract: A Stereospecific Elimination to Form Dehydroamino Acids: Synthesis of the Phomopsin Tripeptide Side Chain.

Michelle M. Stohlmeyer, Hiroko Tanaka, Thomas J. Wandless

Journal:

Year:

1999

File:

PDF, 37 KB

1999

11

ChemInform Abstract: Synthesis of Flavonol Derivatives as Probes of Biological Processes.

Hiroko Tanaka, Michelle M. Stohlmeyer, Thomas J. Wandless, Loverine P. Taylor

Journal:

Year:

2001

File:

PDF, 31 KB

2001

12

Enantioselective Total Synthesis of Ustiloxin D.

Hiroko Tanaka, Andrew M. Sawayama, Thomas J. Wandless

Journal:

Year:

2003

File:

PDF, 59 KB

2003

13

Total Synthesis of Ustiloxin D and Considerations on the Origin of Selectivity of the Asymmetric Allylic Alkylation.

Andrew M. Sawayama, Hiroko Tanaka, Thomas J. Wandless

Journal:

Year:

2005

File:

PDF, 11 KB

2005

14

Engineering small molecule specificity in nearly identical cellular environments

Mark A. Sellmyer, Kryn Stankunas, Roger Briesewitz, Gerald R. Crabtree, Thomas J. Wandless

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 191 KB

english, 2007

15

Synthesis and analysis of stabilizing ligands for FKBP-derived destabilizing domains

Joshua S. Grimley, Denise A. Chen, Laura A. Banaszynski, Thomas J. Wandless

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 126 KB

english, 2008

16

Recent progress with FKBP-derived destabilizing domains

Bernard W. Chu, Laura A. Banaszynski, Ling-chun Chen, Thomas J. Wandless

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 172 KB

english, 2008

17

Conditional Control of Protein Function

Laura A. Banaszynski, Thomas J. Wandless

Journal:

Chemistry & Biology

Year:

2006

Language:

english

File:

PDF, 365 KB

english, 2006

18

Rapamycin Analogs with Differential Binding Specificity Permit Orthogonal Control of Protein Activity

J. Henri Bayle, Joshua S. Grimley, Kryn Stankunas, Jason E. Gestwicki, Thomas J. Wandless, Gerald R. Crabtree

Journal:

Chemistry & Biology

Year:

2006

Language:

english

File:

PDF, 548 KB

english, 2006

19

A General Chemical Method to Regulate Protein Stability in the Mammalian Central Nervous System

Mari Iwamoto, Tomas Björklund, Cecilia Lundberg, Deniz Kirik, Thomas J. Wandless

Journal:

Chemistry & Biology

Year:

2010

Language:

english

File:

PDF, 522 KB

english, 2010

20

Molecular Recognition of Immunophilins and Immunophilin-Ligand Complexes

Stuart L. Schreiber, Jun Lui, Mark W. Albers, Michael K. Rosen, Robert F. Standaert, Thomas J. Wandless, Patricia K. Somers

Journal:

Year:

1992

Language:

english

File:

PDF, 1.02 MB

english, 1992

21

Synthesis of flavonol derivatives as probes of biological processes

Hiroko Tanaka, Michelle M Stohlmeyer, Thomas J Wandless, Loverine P Taylor

Journal:

Tetrahedron Letters

Year:

2000

Language:

english

File:

PDF, 63 KB

english, 2000

22

Synthesis and evaluation of daunorubicin-paclitaxel dimers

Ari K Kar, Patrick D Braun, Thomas J Wandless

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2000

Language:

english

File:

PDF, 320 KB

english, 2000

23

Dicistronic regulation of fluorescent proteins in the budding yeast Saccharomyces cerevisiae

Sarah R. Edwards, Thomas J. Wandless

Journal:

Year:

2010

Language:

english

File:

PDF, 152 KB

english, 2010

24

Meniscal repair in anterior cruciate ligament reconstruction: a long-term outcome study

J. T. K. Melton, J. R. Murray, A. Karim, H. Pandit, F. Wandless, N. P. Thomas

Journal:

Knee Surgery, Sports Traumatology, Arthroscopy

Year:

2011

Language:

english

File:

PDF, 1.76 MB

english, 2011

25

The proteasome makes sense of mixed signals

Wandless, Thomas J

Journal:

Nature Chemical Biology

Year:

2009

Language:

english

File:

PDF, 1.45 MB

english, 2009

26

Erratum: Rapid control of protein level in the apicomplexan Toxoplasma gondii

Agop-Nersesian, Carolina, Münter, Sylvia, Grimley, Joshua S, Wandless, Thomas J, Frischknecht, Friedrich, Herm-Götz, Angelika, Meissner, Markus

Journal:

Year:

2008

Language:

english

File:

PDF, 72 KB

english, 2008

27

Rapid control of protein level in the apicomplexan Toxoplasma gondii

Herm-Götz, Angelika, Agop-Nersesian, Carolina, Münter, Sylvia, Grimley, Joshua S, Wandless, Thomas J, Frischknecht, Friedrich, Meissner, Markus

Journal:

Year:

2007

Language:

english

File:

PDF, 311 KB

english, 2007

28

An inducible translocation strategy to rapidly activate and inhibit small GTPase signaling pathways

Inoue, Takanari, Heo, Won Do, Grimley, Joshua S, Wandless, Thomas J, Meyer, Tobias

Journal:

Year:

2005

Language:

english

File:

PDF, 244 KB

english, 2005

29

Exceptionally high trans (anti) stereoselectivity in catalytic cyclopropanation reactions

Doyle, Michael P., Bagheri, Vahid, Wandless, Thomas J., Harn, Nancy K., Brinker, David A., Eagle, Cassandra T., Loh, Kuo Liang

Journal:

Journal of the American Chemical Society

Year:

1990

Language:

english

File:

PDF, 1.05 MB

english, 1990

30

Enantioselective Total Synthesis of Ustiloxin D

Tanaka, Hiroko, Sawayama, Andrew M., Wandless, Thomas J.

Journal:

Journal of the American Chemical Society

Year:

2003

Language:

english

File:

PDF, 69 KB

english, 2003

31

Evaluation of FKBP and DHFR based destabilizing domains in Saccharomyces cerevisiae

Rishi Rakhit, Sarah R. Edwards, Mari Iwamoto, Thomas J. Wandless

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 612 KB

english, 2011

32

Tunable control of FGF-2 secretion for skeletal tissue engineering

Matthew D. Kwan, Mark A. Sellmyer, Natalina Quarto, Thomas J. Wandless, Michael T. Longaker

Journal:

Journal of the American College of Surgeons

Year:

2008

Language:

english

File:

PDF, 109 KB

english, 2008

33

SH2 domains: A question of independence

Thomas J Wandless

Journal:

Current Biology

Year:

1996

Language:

english

File:

PDF, 88 KB

english, 1996

34

A Rapid, Reversible, and Tunable Method to Regulate Protein Function in Living Cells Using Synthetic Small Molecules

Laura A. Banaszynski, Ling-chun Chen, Lystranne A. Maynard-Smith, A. G. Lisa Ooi, Thomas J. Wandless

Journal:

Year:

2006

Language:

english

File:

PDF, 497 KB

english, 2006

35

Conditional Protein Alleles Using Knockin Mice and a Chemical Inducer of Dimerization

Kryn Stankunas, J.Henri Bayle, Jason E Gestwicki, Yun-Ming Lin, Thomas J Wandless, Gerald R Crabtree

Journal:

Year:

2003

Language:

english

File:

PDF, 476 KB

english, 2003

36

Small-molecule displacement of a cryptic degron causes conditional protein degradation

Bonger, Kimberly M, Chen, Ling-chun, Liu, Corey W, Wandless, Thomas J

Journal:

Nature Chemical Biology

Year:

2011

Language:

english

File:

PDF, 1.26 MB

english, 2011

37

Differential Trafficking of Transport Vesicles Contributes to the Localization of Dendritic Proteins

Sarmad Al-Bassam, Min Xu, Thomas J. Wandless, Don B. Arnold

Journal:

Year:

2012

Language:

english

File:

PDF, 6.38 MB

english, 2012

38

Par-4 Downregulation Promotes Breast Cancer Recurrence by Preventing Multinucleation following Targeted Therapy

Alvarez, James V., Pan, Tien-chi, Ruth, Jason, Feng, Yi, Zhou, Alice, Pant, Dhruv, Grimley, Joshua S., Wandless, Thomas J., DeMichele, Angela, Chodosh, Lewis A.

Journal:

Year:

2013

Language:

english

File:

PDF, 3.30 MB

english, 2013

39

Characterization of the FKBP·Rapamycin·FRB Ternary Complex

Banaszynski, Laura A., Liu, Corey W., Wandless, Thomas J.

Journal:

Journal of the American Chemical Society

Year:

2005

Language:

english

File:

PDF, 345 KB

english, 2005

40

A Stereospecific Elimination to Form Dehydroamino Acids: Synthesis of the Phomopsin Tripeptide Side Chain

Stohlmeyer, Michelle M., Tanaka, Hiroko, Wandless, Thomas J.

Journal:

Journal of the American Chemical Society

Year:

1999

Language:

english

File:

PDF, 42 KB

english, 1999

41

A Bifunctional Molecule That Displays Context-Dependent Cellular Activity

Braun, Patrick D., Barglow, Katherine T., Lin, Yun-Ming, Akompong, Thomas, Briesewitz, Roger, Ray, Gregory T., Haldar, Kasturi, Wandless, Thomas J.

Journal:

Journal of the American Chemical Society

Year:

2003

Language:

english

File:

PDF, 129 KB

english, 2003

42

Inducible control of gene expression with destabilized Cre

Sando, Richard, Baumgaertel, Karsten, Pieraut, Simon, Torabi-Rander, Nina, Wandless, Thomas J, Mayford, Mark, Maximov, Anton

Journal:

Year:

2013

Language:

english

File:

PDF, 1.19 MB

english, 2013

43

Total Synthesis of Ustiloxin D and Considerations on the Origin of Selectivity of the Asymmetric Allylic Alkylation

Sawayama, Andrew M., Tanaka, Hiroko, Wandless, Thomas J.

Journal:

Journal of Organic Chemistry

Year:

2004

Language:

english

File:

PDF, 411 KB

english, 2004

44

Networks of Polarized Actin Filaments in the Axon Initial Segment Provide a Mechanism for Sorting Axonal and Dendritic Proteins

Watanabe, Kaori, Al-Bassam, Sarmad, Miyazaki, Yusuke, Wandless, Thomas J., Webster, Paul, Arnold, Don B.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.38 MB

english, 2012

45

Affinity Modulation of Small-Molecule Ligands by Borrowing Endogenous Protein Surfaces

Roger Briesewitz, Gregory T. Ray, Thomas J. Wandless and Gerald R. Crabtree

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.91 MB

english, 1999

46

Characterization of the FKBP·Rapamycin·FRB Ternary Complex [ J. Am. Chem. Soc. 2005 , 127 , 4715−4721].

Banaszynski, Laura A., Liu, Corey W., Wandless, Thomas J.

Journal:

Journal of the American Chemical Society

Year:

2006

Language:

english

File:

PDF, 147 KB

english, 2006

47

Quantitative Analyses of Bifunctional Molecules †

Braun, Patrick D., Wandless, Thomas J.

Journal:

Year:

2004

Language:

english

File:

PDF, 100 KB

english, 2004

48

Efficient Synthesis of β,γ-Dehydrovaline

Woiwode, Thomas F., Wandless, Thomas J.

Journal:

Journal of Organic Chemistry

Year:

1999

Language:

english

File:

PDF, 65 KB

english, 1999

49

General Method for Regulating Protein Stability with Light

Bonger, Kimberly M., Rakhit, Rishi, Payumo, Alexander Y., Chen, James K., Wandless, Thomas J.

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 2.97 MB

english, 2014

50

Study of receptor-ligand interactions through receptor labeling and isotope-edited NMR

Rosen, Michael K., Michnick, Stephen W., Wandless, Thomas J., Schrieber, Stuart L.

Journal:

Journal of Organic Chemistry

Year:

1991

Language:

english

File:

PDF, 876 KB

english, 1991

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